(Potassium Iodide Oral Solution, USP) 1 g/mL

When tenacious mucus complicates the problem



  • Used to treat patients with chronic pulmonary diseases like asthma and COPD1
  • Used as an expectorant in the symptomatic treatment of chronic pulmonary diseases where tenacious mucus complicates the problem, including bronchial asthma, bronchitis, and pulmonary emphysema1
  • The dosing is 300 to 600 mg per day diluted in one glassful of water, fruit juice or milk taken 3 to 4 times daily1
  • Patients pay as little as $0 co-pay with our new eVoucherRx™ Program. No coupon needed. Discount automatically applied at the pharmacy.


SSKI® is available at pharmacies nationwide. For assistance finding this medication, please contact us.




  • Potassium iodide can cause fetal harm, abnormal thyroid function, and goiter when administered to a pregnant woman. Because of the possible development of fetal goiter, if the drug is used during pregnancy or if the patient becomes pregnant during therapy, apprise the patient of the potential hazard.

  • Precautions

  • General: In some patients, prolonged use of iodides can lead to hypothyroidism. Iodides should be used with caution in patients having Addison’s disease, cardiac disease, hyperthyroidism, myotonia congenita, tuberculosis, acute bronchitis, or renal function impairment.

  • Drug Interactions: Concurrent use with lithium or antithyroid drugs may potentiate the hypothyroid and goitrogenic effects of these medications. Concurrent use with potassiumcontaining medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest.

  • Drug/Laboratory Test Interactions: Thyroid function tests may be altered by iodide.

  • Pregnancy: Category D – see “Warnings” section.

  • Nursing Mothers: Potassium iodide is excreted in breast milk. Use by nursing mothers may cause skin rash and thyroid suppression in the infant.

  • Pediatric Use: Safety and effectiveness in children have not
    been established.

  • Adverse Reactions: The most frequent adverse reactions to potassium iodide are stomach upset, diarrhea, nausea, vomiting, stomach pain, skin rash, and salivary gland swelling or tenderness. Less frequent adverse reactions include gastrointestinal bleeding, confusion, irregular heartbeat, numbness, tingling, pain or weakness in hands or feet, unusual tiredness, weakness or heaviness of legs, fever, and swelling of neck or throat. Thyroid adenoma, goiter, and myxedema are possible side effects. Iodism or chronic iodine poisoning may occur during prolonged treatment or with the use of high doses. The symptoms of iodism include burning of mouth or throat, severe headache, metallic taste, soreness of teeth and gums, symptoms of head cold, irritation of the eyes with swelling of the eyelids, unusual increase in salivation, acneform skin lesions in the seborrheic areas, and rarely, severe skin eruptions. If symptoms of iodism appear, the drug should be withdrawn and the patient given appropriate
    supportive therapy.

  • Hypersensitivity to iodides may occur and may be manifested by angioedema, cutaneous and mucosal hemorrhage, and signs and symptoms resembling serum sickness, such as fever, arthralgia, lymph node enlargement, and eosinophilia.

  • Overdosage: Acute toxicity from potassium iodide is relatively rare. An occasional individual may show marked sensitivity and the onset of acute poisoning can occur immediately or hours after administration. Angioedema, laryngeal edema and cutaneous hemorrhages may occur. Iodism or chronic iodine poisoning may occur during prolonged treatment or with the use of high doses. Symptoms of iodism typically disappear soon after discontinuation of the drug. Abundant fluid and salt intake aids in iodide elimination.

  • Dosage and Administration
    Adults – 0.3 mL (300 mg) or 0.6 mL (600 mg) diluted in one glassful of water, fruit juice or milk 3 to 4 times daily. To minimize gastric irritation, take with food or milk.
    This medication should be used no longer than necessary to produce the desired effect.

  • How Supplied: SSKI® (potassium iodide oral solution, USP) is supplied in 1 fluid ounce (30 mL) bottles (NDC 71740-112-30) with a calibrated dropper marked to deliver 0.3 mL (300 mg) and 0.6 mL (600 mg); and 8 fluid ounce (237 mL) bottles (NDC 71740-112-08). Inactive ingredient: Sodium thiosulfate as a preservative.

  • Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature]. Keep tightly closed and protected from light.

SSKI® is available at pharmacies nationwide. For assistance in finding this medication, please contact us.

For more information, talk with your healthcare provider.

Please see the full Prescribing Information for SSKI and discuss it with your healthcare provider. See for the SSKI package insert. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

850 Shades Creek Parkway, Suite 320, 
Birmingham, AL  35209
Phone: 800-528-3058

To report suspected adverse reactions, contact Avondale Pharmaceuticals at (800) 528-3058