(Niacin Tablets, USP) 500 mg

Managing cholesterol can be difficult, but Niacor® can help.

NIACOR is a prescription medication used along with diet and exercise when diet and exercise alone have been unsuccessful. What NIACOR means to you:

  • With proper diet and exercise, NIACOR works to help lower LDL (“bad”) cholesterol and help raise HDL (“good”) cholesterol in people with abnormal cholesterol levels, and lower triglycerides (“fats”) in your blood.
  • Severe liver damage has occurred when switching from a product like NIACOR to a long-acting niacin, like Niaspan®1.
  • Niacor can help slow down or lessen plaque buildup.
    Plaque buildup (fatty deposits) is a complex process and has a number of risk factors that lead up to it, including a family history of early heart disease, high blood pressure, smoking, diabetes, and abnormal cholesterol levels. Cholesterol and other substances can build up in the walls of the heart’s arteries resulting in plaque. NIACOR can slow or even help clear away some plaque that builds on artery walls of the heart-when used in combination with diet and a bile acid-binding resin (another cholesterol medication) in patients who have a history of coronary artery disease and high cholesterol levels.


NIACOR® is available at pharmacies nationwide. For assistance finding this medication, please contact us.


Safety Considerations

NIACOR is not for people with liver problems, stomach ulcers, bleeding problems, or those allergic to any product ingredient. Important Safety Information and Uses You Should Know About NIACOR® (niacin immediate-release) tablets


  • NIACOR is not for people with liver problems, stomach ulcers, serious bleeding problems, or those allergic to any product ingredient.
  • Tell your healthcare provider about any unexplained muscle pain, tenderness, or weakness, as this could be a sign of a serious side effect. This risk increases when NIACOR is taken, particularly in the elderly, diabetics, and those with kidney or thyroid problems.
  • NIASPAN should be used with caution if you consume large amounts of alcohol and/or have a past history of liver disease.
  • Your healthcare provider should do blood tests before and during treatment to check liver enzyme levels, as these can increase with treatment.
  • NIACOR can cause an increase in blood sugar levels. If you have diabetes, check your blood sugar levels more frequently during the first few months or with NIACOR dose changes.
  • Tell your healthcare provider if you have kidney problems or a history of gout. NIACOR can cause an increase in uric acid levels.
  • The most common side effects with NIACOR are flushing, diarrhea, nausea, vomiting, increased cough, and itching.
  • Flushing (warmth, redness, itching, and/or tingling of the skin) is a common side effect of NIACOR therapy. It may vary in severity and is more likely to happen when starting NIACOR or during dose increases. Flushing may get better after several weeks of consistent NIACOR use. Talk to your doctor about how the symptoms of flushing are different from symptoms of a heart attack. By dosing at bedtime, flushing will likely occur during sleep.
  • If awakened by flushing, get up slowly, especially if feeling dizzy or faint, or taking blood pressure medications. If you are taking another cholesterol medication called a bile acid-binding resin (e.g., colestipol, cholestyramine) along with NIACOR, take these medicines at least 4 to 6 hours apart.
  • Some medicines should not be taken with NIACOR. Tell your healthcare provider about all the medicines you take, including aspirin, any cholesterol medication, blood pressure medication, blood thinner medication, or any products containing niacin or nicotinamide.

NIACOR® is available at pharmacies nationwide. For assistance finding this medication, please contact us.

For more information, talk with your healthcare provider. Taking NIACOR with another cholesterol-lowering medicine (simvastatin) does not reduce heart attacks or strokes more than taking simvastatin alone.

1. Niaspan [package insert].
2. NIACOR [package insert].

Please see the full Prescribing Information for NIACOR and discuss it with your healthcare provider. See for the Niacor package insert. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

850 Shades Creek Parkway, Suite 320, 
Birmingham, AL  35209
Phone: 800-528-3058

To report suspected adverse reactions, contact Avondale Pharmaceuticals at (800) 528-3058